Immunoengineering

This course will first provide an understanding of basic immunology and then transition to apply these fundamental principles to the design of immunoengineering solutions to biomedical disease challenges. Basic immunological principles that we will cover in the first part of the course include the cells of the immune system and their function, innate and adaptive responses, antigen presentation, T and B cell responses, and immunological memory. In the second part of the course, we will focus on understanding how these basic principles are applied in the design of immunomodulatory nanomaterials, antibody engineering, systems immunology, and development of cell-based therapies. This application-oriented second part of the course will involve overviews of the scientific literature to cover this rapidly evolving field. Throughout the course, we will focus on the biomedical challenges of cancer and infectious disease.